drug resistance of acinetobacter in selected hospitals

نویسندگان

davood yadegarynia infectious diseases and tropical medicine research center, shahid beheshti university of medical sciences, tehran, ir iran

mansoureh khalili azad infectious diseases and tropical medicine research center, shahid beheshti university of medical sciences, tehran, ir iran

latif gachkar infectious diseases and tropical medicine research center, shahid beheshti university of medical sciences, tehran, ir iran

sara rahmati roodsari infectious diseases and tropical medicine research center, shahid beheshti university of medical sciences, tehran, ir iran

چکیده

background: nowadays, nosocomial infection with multidrug-resistant acinetobacter is an important problem in the world, which is facing wide spectrum antibiotics and hence has become resistant. m aterials and methods: in this study, positive cultures of acinetobacter from one hundred clinical samples in seven hospitals from tehran during 2012-2013 were collected for checking antibiotic susceptibility. samples test with ceftazidim, cefepime, amikacine and imipenem by e-test and for tazocin, colistin and tigecycline was performed with disk diffusion method. r es ults: for colistin 10 samples, and for tazocin, 40 samples were performed by e-test method. then boumannii species of bacteria and non- baumannii acinetobacter were separated by pcr and antibiotic susceptibility testing was performed on them. 89% of acinetobacter samples were boumannii species, which was isolated from respiratory secretions at icu. c onclusion: boumannii and non-boumannii species of bacteria with a high percentage were resistant to ceftazidim, amikacine, cefepime, tazocin and imipenem. all baumannii and non-boumannii acinetobacter were sensitive to colistin, were only 75% sensitive to tigecycline, which is a new glycylcycline. colistin and tazocin results in samples limited to the e-test method were similar with disk diffusion.

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novelty in biomedicine

جلد ۳، شماره ۳، صفحات ۱۰۳-۱۱۰

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